human TP53 ORF clone (NM_001126116.1)

Name: human TP53 ORF clone (NM_001126116.1)
SKU: CDCH095474
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH095474

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Product Information

Gene Information

Cat. No.	CDCH095474
Description	Homo sapiens tumor protein p53 (TP53), transcript variant 6, mRNA.
Product Type	ORF clone
Gene Abbr	TP53
Gene Name	TP53 tumor protein p53 [ Homo sapiens ]
Species	Human
ORF Size	630bp
Format	purified plasmid or bacterial stock
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Gene Name	TP53 tumor protein p53 [ Homo sapiens ]
Gene Symbol	TP53
Synonyms	P53; BCC7; LFS1; TRP53
Gene Description	tumor protein p53 (Li-Fraumeni syndrome)
Gene ID	7157
Uni Prot ID	P04637
m RNA Refseq	NM_001126115.1
Protein Refseq	NP_001119587.1
Chromosome Location	17p13.1
Function	ATP binding; DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription factor binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chaperone binding; chromatin binding; copper ion binding; damaged DNA binding; enzyme binding; histone acetyltransferase binding; histone deacetylase regulator activity; identical protein binding; p53 binding; protease binding; protein N-terminus binding; protein binding; protein heterodimerization activity; protein kinase binding; protein phosphatase 2A binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding; ubiquitin protein ligase binding; zinc ion binding;
Pathway	AMPK signaling, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Activation of NOXA and translocation to mitochondria, organism-specific biosystem; Activation of PUMA and translocation to mitochondria, organism-specific biosystem; Alzheimers Disease, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem;
MIM	191170

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