Recombinant Mouse Tnfrsf18 (C-Fc-6His)

Name: Recombinant Mouse Tnfrsf18 (C-Fc-6His)
SKU: RP00649
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00649 Tag : C-Fc-6His

Expressed Region : Ser22-His153 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00649
Description	Recombinant Mouse Tnfrsf18 (C-Fc-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ser22-His153 with a Fc-6His tag at the C terminus.
Species	Mouse
Tag	C-Fc-6His
Mol Weight	42.3 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Ser22-His153
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 5% Sucrose, 5% Dextran-70，0.05% Tween 80, pH8.0.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Tnfrsf18
Background	This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Synonyms	Tumor necrosis factor receptor superfamily member 18;Glucocorticoid-induced TNFR-related protein;Tnfrsf18; AITR;CD357;GITR-D;TNFRSF18

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