Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : VAR-021
| Cat. No. | VAR-021 |
| Description | Lipid A is a lipid component of an endotoxin held responsible for the toxicity of gram-negative bacteria. It is the innermost of the three regions of the lipopolysaccharide (LPS), also called endotoxin molecule, and its hydrophobic nature allows it to anchor the LPS to the outer membrane. Lipid A (and LPS) has been demonstrated to activate cells via Toll-like receptor 4 (TLR4), MD-2 and CD14 on the cell surface. They are being developed as drugs for the treatment of excessive inflammatory responses to infections with gram-negative bacteria. |
| Product Type | Bacteria-derived Adjuvant |
| Stability | Stable for at least 2 years after receipt when stored at 4°C. |
| Purity | ≥99% |
| Storage | Store at 4°C; |
A: No, the reagent is only toxic to gram-negative bacteria and does not have inhibitory effects on gram-positive bacteria.
A: No, the reagent is only for scientific research and cannot be used for other purposes.
A: The reagent can be stored at 4°C for at least 2 years.
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Lipid A from S. minnesota R595 can activate cells through Toll-like receptor 4 (TLR4), MD-2, and CD14 on the cell surface.
The reagent can be used in experiments related to gram-negative bacteria resistance, and is sometimes used as a positive control.
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