Humanized CXCR4 Murine Tumor Cell Line

Name: Humanized CXCR4 Murine Tumor Cell Line
SKU: CSC-RH0052M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0052M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0052M
Description	These transgenic cells carry humanized CXCR4 and form solid tumors in vivo. The endogenous mouse Cxcr4 gene was replaced by human CXCR4 gene.
Target Gene	CXCR4
Alias	CD184, D2S201E, FB22, HM89
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CXCR4 chemokine (C-X-C motif) receptor 4 [ Homo sapiens ]
Gene Symbol	CXCR4
Synonyms	FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E
Gene Description	chemokine (C-X-C motif) receptor 4
GeneID	7852
Uni ProtID	P61073
mRNA Refseq	NM_001008540.1
Protein Refseq	NP_001008540.1
Chromosome Location	2q21
Function	C-X-C chemokine receptor activity; G-protein coupled receptor activity; actin binding; coreceptor activity; myosin light chain binding; protein binding; ubiquitin binding; ubiquitin protein ligase binding;
Pathway	Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Binding and entry of HIV virion, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem;
MIM	162643

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