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Rat CXCR4 ORF clone(NM_022205.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL183857

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Product Information

Gene Information

Cat. No. CDCL183857
Description ORF Clone of Rattus norvegicus chemokine (C-X-C motif) receptor 4 DNA.
Product Type ORF clone
Gene Abbr CXCR4
Species Rat
ORF Size 1050bp
Vector pGEM-T
Warning This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage store at -20°C
Target Gene CXCR4
Background This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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