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shRNA set against Human CXCR4 (NM_003467.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH272289

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Gene Information

Cat. No. SHH272289
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CXCR4
Gene Name CXCR4 chemokine (C-X-C motif) receptor 4 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CXCR4 chemokine (C-X-C motif) receptor 4 [ Homo sapiens ]
Gene Symbol CXCR4
Synonyms FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E
Gene Description chemokine (C-X-C motif) receptor 4
Gene ID 7852
Uni Prot ID P61073
m RNA Refseq NM_001008540.1
Protein Refseq NP_001008540.1
Chromosome Location 2q21
Function C-X-C chemokine receptor activity; G-protein coupled receptor activity; actin binding; coreceptor activity; myosin light chain binding; protein binding; ubiquitin binding; ubiquitin protein ligase binding;
Pathway Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Binding and entry of HIV virion, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem;
MIM 162643
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