Humanized CCR4 Murine Tumor Cell Line

Name: Humanized CCR4 Murine Tumor Cell Line
SKU: CSC-RH0084M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0084M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0084M
Description	These transgenic cells carry humanized CCR4 and form solid tumors in vivo. The endogenous mouse Ccr4 gene was replaced by human CCR4 gene.
Target Gene	CCR4
Alias	CC-CKR-4, CD194, CKR4, CMKBR4
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CCR4 chemokine (C-C motif) receptor 4 [ Homo sapiens ]
Gene Symbol	CCR4
Synonyms	CKR4; K5-5; CD194; CMKBR4; ChemR13; CC-CKR-4; HGCN:14099
Gene Description	chemokine (C-C motif) receptor 4
Gene ID	1233
Uni Prot ID	A0N0Q1
m RNA Refseq	NM_005508.4
Protein Refseq	NP_005499.1
Chromosome Location	3p24
Function	C-C chemokine receptor activity; chemokine receptor activity;
Pathway	Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem;
MIM	604836

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