Recombinant Human CXCR4 (N-Fc)

Name: Recombinant Human CXCR4 (N-Fc)
SKU: RP00257

Cat.No. : RP00257 Tag: N-Fc

Expressed Region: Met1-Ser46 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00257
Description	The Recombinant Human CXCR4 (N-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Met1-Ser46 with a Fc tag at the N terminus.
Species	Human
Tag	N-Fc
Mol. Weight	30.6 KDa
Expressed Region	Met1-Ser46
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 100mM Glycine, pH7.5.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	CXCR4
Background	This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms	CXCR4,CD184,Fusin,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM

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