Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : VNTH-7
| Cat. No. | VNTH-7 |
| Description | Cre-conditional, replication-incompetent anterograde monosynaptic HSV-1 H129 tracer (H361 strain design). The TK gene is deleted and replaced by a Cre-activated LoxP-Stop-LoxP (LSL) cassette driving tdTomato expression. Without Cre, no tdTomato is produced and the virus cannot replicate. When combined with Cre-expressing animals and an AAV-DIO-TK helper virus, Cre excises the STOP, tdTomato is expressed in Cre+ starter neurons, and TK complementation from the helper AAV enables a single round of replication and anterograde spread across one synapse, specifically labeling the direct postsynaptic targets of Cre+ neurons. |
| Product Type | Herpes simplex virus |
| Reporter | tdTomato |
| Synaptic Transmission | Mono-synaptic (single-step, Cre-restricted, with AAV-DIO-TK helper) |
| TKStatus | TK-deleted (ΔTK, replication-incompetent alone) |
| Applications |
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| Size | Custom |
| Storage | Store at -80℃. Avoid multiple freeze/thaw cycles. |
| Shipping | Dry ice |
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