Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : VNTH-4
| Cat. No. | VNTH-4 |
| Description | Replication-incompetent anterograde monosynaptic HSV-1 H129 tracer with the thymidine kinase (TK, UL23) gene deleted. The tdTomato reporter is expressed under the human ubiquitin C (hUbC) promoter. Because TK is essential for viral genome replication in neurons, this tracer cannot replicate or cross synapses on its own. When co-injected at the same site with an AAV helper virus (e.g., AAV-EF1α-TK) that provides TK in trans, the tracer replicates only in AAV-TK-transduced starter neurons and crosses a single synapse to label directly postsynaptic neurons, enabling precise monosynaptic output mapping. |
| Product Type | Herpes simplex virus |
| Reporter | tdTomato |
| Synaptic Transmission | Mono-synaptic (single-step, with AAV-TK helper) |
| TKStatus | TK-deleted (ΔTK, replication-incompetent alone) |
| Applications |
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| Size | Custom |
| Storage | Store at -80℃. Avoid multiple freeze/thaw cycles. |
| Shipping | Dry ice |
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