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Rat Trim27 ORF Clone(NM_001134974.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR377084

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Gene Information

Cat. No. CDCR377084
Product Type ORF Clone
Gene Abbr Trim27
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1542 bp
Vector pCMV6-Entry
Target Gene RFP
Background This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq, Jul 2008]
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