Pages
Products

Rat Mre11a ORF Clone(NM_022279.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378965

Inquire for Price

Product Information

Gene Information

Cat. No. CDCR378965
Product Type ORF Clone
Gene Abbr Mre11a
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2121 bp
Vector pCMV6-Entry
Target Gene Mre11a
Background Enables nuclease activity. Involved in DNA strand resection involved in replication fork processing; chromosome organization; and double-strand break repair via homologous recombination. Acts upstream of or within several processes, including double-strand break repair; homologous chromosome pairing at meiosis; and mitotic DNA damage checkpoint signaling. Located in PML body. Part of Mre11 complex. Colocalizes with chromosome, telomeric region. Is expressed in cerebral cortex and telencephalon. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome; ataxia-telangiectasia-like disorder-1; endometrial cancer; gastrointestinal system cancer (multiple); and urinary bladder cancer. Orthologous to human MRE11 (MRE11 homolog, double strand break repair nuclease). [provided by Alliance of Genome Resources, Feb 2025]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction