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Panoply™ Human MRE11A Knockdown Stable Cell Line

Cat.No.
CSC-DC009702
Panoply™ Human MRE11A Knockdown Stable Cell Line
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
MRE11A
ATLD; HNGS1; MRE11; MRE11B
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
P49959
11q21
3-5 exonuclease activity; contributes_to ATP-dependent DNA helicase activity; contributes_to DNA binding; double-stranded DNA binding; endodeoxyribonuclease activity; manganese ion binding; nuclease activity; protein C-terminus binding; protein binding; single-stranded DNA specific endodeoxyribonuclease activity;
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; DNA Repair, organism-specific biosystem; DNA damage response, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem;

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