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Mre11a


Official Full Name
MRE11A homolog A, double strand break repair nuclease
Organism
Mus musculus
Gene ID
17535
Background
Enables nuclease activity. Involved in DNA strand resection involved in replication fork processing; chromosome organization; and double-strand break repair via homologous recombination. Acts upstream of or within several processes, including double-strand break repair; homologous chromosome pairing at meiosis; and mitotic DNA damage checkpoint signaling. Located in PML body. Part of Mre11 complex. Colocalizes with chromosome, telomeric region. Is expressed in cerebral cortex and telencephalon. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome; ataxia-telangiectasia-like disorder-1; endometrial cancer; gastrointestinal system cancer (multiple); and urinary bladder cancer. Orthologous to human MRE11 (MRE11 homolog, double strand break repair nuclease). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Mre11a; Mre11; Mre11b

Cat.No. Product Name Price
AD10132Z Human MRE11A adenoviral particles Inquiry
Cat.No. Product Name Price
SHH197919 shRNA set against Human MRE11A(NM_005591.3) Inquiry
SHH197937 shRNA set against Human MRE11A(NM_005590.3) Inquiry
SHH344216 shRNA set against Human MRE11A (NM_005590.3) Inquiry
SHH344224 shRNA set against Rat MRE11A (NM_022279.1) Inquiry
SHH197903 shRNA set against Mouse Mre11a(NM_018736.2) Inquiry
SHH197957 shRNA set against Rat Mre11a(NM_022279.1) Inquiry
SHH332231 shRNA set against Rat LOC498675 (NM_001109113.1) Inquiry
SHH344220 shRNA set against Mouse MRE11A (NM_018736.2) Inquiry
SHW005285 shRNA set against Chicken MRE11A (NM_204778) Inquiry
SHW006098 shRNA set against Danio rerio MRE11A (NM_001001407) Inquiry
Cat.No. Product Name Price
CDCS412337 Human MRE11A ORF Clone (BC005241) Inquiry
MiUTR1H-06414 MRE11A miRNA 3'UTR clone Inquiry
MiUTR1H-06413 MRE11A miRNA 3'UTR clone Inquiry
CDFR011962 Rat Mre11a cDNA Clone(NM_022279.1) Inquiry
CDFR008659 Rat LOC498675 cDNA Clone(NM_001109113.1) Inquiry
CDFH011726 Human MRE11A cDNA Clone(NM_005591.3) Inquiry
CDFH011725 Human MRE11A cDNA Clone(NM_005591.3) Inquiry
CDFH011724 Human MRE11A cDNA Clone(NM_005590.3) Inquiry
MiUTR1R-03973 MRE11A miRNA 3'UTR clone Inquiry
CDCR378965 Rat Mre11a ORF Clone(NM_022279.1) Inquiry
CDCR290853 Human MRE11A ORF Clone(NM_005591.3) Inquiry
CDCL133825 Mouse Mre11a ORF clone (NM_018736.2) Inquiry
CDCL133821 Human MRE11A ORF clone (NM_005590.3) Inquiry
MiUTR1M-07242 MRE11A miRNA 3'UTR clone Inquiry
CDCR375736 Rat LOC498675 ORF Clone(NM_001109113.1) Inquiry
CDCB183758 Rabbit MRE11A ORF clone (XM_008262535.1) Inquiry
CDCB167573 Danio rerio MRE11A ORF Clone (NM_001001407) Inquiry
CDCB166760 Chicken MRE11A ORF Clone (NM_204778) Inquiry
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