Pages
Products

Human KIR2DL1 Stable Cell Line - CHO-K1

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RO0207

Host Cell :   CHO-K1 Size :   >1x106 frozen cells/vial

Inquire for Price

Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No. CSC-RO0207
Description This cell line is engineered to stably overexpress the human KIR2DL1 in CHO-K1 cells.
Introduction This cell line is constructed by transfection of human killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 (KIR2DL1) into CHO-K1, followed by stable cell selection. The expression of KIR2DL1 has been analyzed through flow cytometry.
Target Gene KIR2DL1
Gene Species Homo sapiens (Human)
Host Cell CHO-K1
Host Cell Species Cricetulus griseus (Chinese hamster)
Applications

1. Studying the interactions between immune cells and cancer cells

2. Studying the mechanisms of resistance to immune checkpoint blockade

3. High-throughput screening

4. Drug target validation

Size >1x106 frozen cells/vial
Stability Validated for at least 10 passages
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid nitrogen
Shipping Dry ice
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 [ Homo sapiens ]
Gene Symbol KIR2DL1
Synonyms NKAT; NKAT1; p58.1; CD158A; KIR221; KIR-K64
Gene Description killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
Gene ID 3802
Uni Prot ID P43626
m RNA Refseq NM_014218.2
Protein Refseq NP_055033.2
Chromosome Location 19q13.4
Function protein binding; receptor activity;
Pathway Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; DAP12 interactions, organism-specific biosystem; Graft-versus-host disease, organism-specific biosystem; Graft-versus-host disease, conserved biosystem; Immune System, organism-specific biosystem;
MIM 604936
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction