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shRNA set against Mouse TLR3 (NM_126166.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH427976

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Gene Information

Cat. No. SHH427976
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr TLR3
Gene Name Tlr3 toll-like receptor 3 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Tlr3 toll-like receptor 3 [ Mus musculus ]
Gene Symbol Tlr3
Synonyms AI957183
Gene Description toll-like receptor 3
GeneID 142980
Uni ProtID Q99MB1
mRNA Refseq NM_126166.4
Protein Refseq NP_569054.2
Chromosome Location 8; 8 B2
Function RNA binding; double-stranded RNA binding; protein binding; receptor activity;
Pathway Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; Hepatitis B, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem;
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