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TLR3


Official Full Name
toll like receptor 3
Organism
Homo sapiens
Gene ID
7098
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It thus plays a role in host defense against multiple viruses. [provided by RefSeq, Jul 2021]
Synonyms
CD283; IIAE2; IMD83

Cat.No. Product Name Price
CDCB162300 Chicken TLR3 ORF Clone (NM_001011691) Inquiry
CDCL186472 Human TLR3 ORF clone(NM_003265.2) Inquiry
CDCL186473 Mouse TLR3 ORF clone(NM_126166.4) Inquiry
CDCS411221 Human TLR3 ORF Clone (BC096333) Inquiry
CDFH019711 Human TLR3 cDNA Clone(NM_003265.2) Inquiry
CDFR015195 Rat Tlr3 cDNA Clone(NM_198791.1) Inquiry
MiUTR1H-10435 TLR3 miRNA 3'UTR clone Inquiry
MiUTR1M-11793 TLR3 miRNA 3'UTR clone Inquiry
MiUTR1R-08036 TLR3 miRNA 3'UTR clone Inquiry
CDCB156615 Cynomolgus TLR3 ORF clone Inquiry
CDCB169437 Danio rerio TLR3 ORF Clone (NM_001013269) Inquiry
CDCB180560 Rabbit TLR3 ORF clone (XM_008273952.1) Inquiry
CDCR382246 Rat Tlr3 ORF Clone(NM_198791.1) Inquiry
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