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Panoply™ Human TLR3 Knockdown Stable Cell Line

Cat.No.
CSC-DC016002
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
TLR3
Synonyms
CD283; IIAE2
Gene Description
toll-like receptor 3
Gene ID
UniProt ID
E6Y0F1
mRNA Refseq
Protein Refseq
Chromosome Location
4q35
Function
double-stranded RNA binding; double-stranded RNA binding; receptor activity; transmembrane signaling receptor activity;
Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; Hepatitis B, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem;
MIM

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