shRNA set against Mouse NOTCH1 (NM_008714.3)

Name: shRNA set against Mouse NOTCH1 (NM_008714.3)
SKU: SHH353820
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH353820

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Product Information

Gene Information

Cat. No.	SHH353820
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	NOTCH1
Gene Name	Notch1 notch 1 [ Mus musculus ]
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Notch1 notch 1 [ Mus musculus ]
Gene Symbol	NOTCH1
Synonyms	N1; Mis6; Tan1; lin-12; 9930111A19Rik
GeneID	18128
Uni ProtID	Q01705
mRNA Refseq	NM_008714.3
Protein Refseq	NP_032740.3
Chromosome Location	2 A3; 2 15.0 cM
Function	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; calcium ion binding; chromatin DNA binding; chromatin binding; core promoter binding; enzyme binding; enzyme inhibitor activity; metal ion binding; protein binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Pathway	Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Dorso-ventral axis formation, organism-specific biosystem; Dorso-ventral axis formation, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Heart Development, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem; Notch-HLH transcription pathway, organism-specific biosystem; PluriNetWork, organism-specific biosystem; Pre-NOTCH Expression and Processing, organism-specific biosystem; Pre-NOTCH Processing in Golgi, organism-specific biosystem; Pre-NOTCH Processing in the Endoplasmic Reticulum, organism-specific biosystem; Pre-NOTCH Transcription and Translation, organism-specific biosystem; Prion diseases, organism-specific biosystem; Prion diseases, conserved biosystem; Ptf1a related regulatory pathway, organism-specific biosystem; Regulation of beta-cell development, organism-specific biosystem; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem;

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