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shRNA set against Rat Notch1(NM_001105721.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHR008426

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Gene Information

Cat. No. SHR008426
Description Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr Notch1
Gene Name Notch1 notch 1 [ Rattus norvegicus ]
Species Rat
Report Gene eGFP
Content Each set contains 4 shRNA expression constructs.
Promoter H1
Selection Marker Puromycin
Format 5 μg purified plasmid
Unit Size 5 μg
Gene Name Notch1 notch 1 [ Rattus norvegicus ]
Gene Symbol Notch1
Synonyms TAN1; NOTCH
Gene Description Notch gene homolog 1 (Drosophila)
GeneID 25496
mRNA Refseq NM_001105721.1
Protein Refseq NP_001099191.1
Chromosome Location 3p13
Function RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; calcium ion binding; chromatin DNA binding; chromatin binding; core promoter binding; core promoter binding; core promoter binding; enzyme binding; enzyme binding; enzyme binding; enzyme inhibitor activity; enzyme inhibitor activity; enzyme inhibitor activity; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Pathway Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Dorso-ventral axis formation, organism-specific biosystem; Dorso-ventral axis formation, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem;
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