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shRNA set against Human PTCH1(NM_001083603.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHR149910

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Gene Information

Cat. No. SHR149910
Description Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr PTCH1
Gene Name PTCH1 patched 1 [ Homo sapiens ]
Species Human
Report Gene eGFP
Content Each set contains 4 shRNA expression constructs.
Promoter H1
Selection Marker Puromycin
Format 5 μg purified plasmid
Unit Size 5 μg
Gene Name PTCH1 patched 1 [ Homo sapiens ]
Gene Symbol PTCH1
Synonyms PTC; BCNS; HPE7; PTC1; PTCH; NBCCS; PTCH11
Gene Description patched homolog 1 (Drosophila)
Gene ID 5727
Uni Prot ID Q13635
m RNA Refseq NM_000264.3
Protein Refseq NP_000255.2
Chromosome Location 9q22.3
Function cholesterol binding; cyclin binding; hedgehog family protein binding; hedgehog receptor activity; heparin binding; patched binding; protein binding; protein complex binding; smoothened binding;
Pathway Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Glypican 3 network, organism-specific biosystem; Hedgehog Signaling Pathway, organism-specific biosystem;
MIM 601309
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