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PTCH1


Official Full Name
patched 1
Organism
Homo sapiens
Gene ID
5727
Background
This gene encodes a member of the patched family of proteins and a component of the hedgehog signaling pathway. Hedgehog signaling is important in embryonic development and tumorigenesis. The encoded protein is the receptor for the secreted hedgehog ligands, which include sonic hedgehog, indian hedgehog and desert hedgehog. Following binding by one of the hedgehog ligands, the encoded protein is trafficked away from the primary cilium, relieving inhibition of the G-protein-coupled receptor smoothened, which results in activation of downstream signaling. Mutations of this gene have been associated with basal cell nevus syndrome and holoprosencephaly. [provided by RefSeq, Aug 2017]
Synonyms
PTC; BCNS; PTC1; PTCH; BCNS1; NBCCS; SLC65B1

Cat.No. Product Name Price
SHH385820 shRNA set against Human PTCH1 (NM_000264.3) Inquiry
SHR149910 shRNA set against Human PTCH1(NM_001083603.1) Inquiry
SHW005462 shRNA set against Chicken PTCH1 (NM_204960) Inquiry
SHH385824 shRNA set against Mouse PTCH1 (NM_008957.2) Inquiry
SHR149820 shRNA set against Human PTCH1(NM_000264.3) Inquiry
SHR149856 shRNA set against Human PTCH1(NM_001083602.1) Inquiry
SHR149874 shRNA set against Human PTCH1(NM_001083604.1) Inquiry
SHR149892 shRNA set against Mouse Ptch1(NM_008957.2) Inquiry
SHR149946 shRNA set against Rat Ptch1(NM_053566.1) Inquiry
Cat.No. Product Name Price
CDFH015444 Human PTCH1 cDNA Clone(NM_001083603.1) Inquiry
MiUTR1H-08405 PTCH1 miRNA 3'UTR clone Inquiry
MiUTR1H-08404 PTCH1 miRNA 3'UTR clone Inquiry
MiUTR1H-08403 PTCH1 miRNA 3'UTR clone Inquiry
CDFR013289 Rat Ptch1 cDNA Clone(NM_053566.1) Inquiry
CDFL010996 Mouse Ptch1 cDNA Clone(NM_008957.2) Inquiry
CDFH015449 Human PTCH1 cDNA Clone(NM_001083605.1) Inquiry
CDFH015448 Human PTCH1 cDNA Clone(NM_001083604.1) Inquiry
CDFH015447 Human PTCH1 cDNA Clone(NM_001083602.1) Inquiry
CDFH015446 Human PTCH1 cDNA Clone(NM_001083607.1) Inquiry
CDFH015445 Human PTCH1 cDNA Clone(NM_001083606.1) Inquiry
MiUTR1H-08406 PTCH1 miRNA 3'UTR clone Inquiry
MiUTR1M-09722 PTCH1 miRNA 3'UTR clone Inquiry
CDCB190736 Rabbit PTCH1 ORF clone (XM_008257683.1) Inquiry
CDCR380326 Rat Ptch1 ORF Clone(NM_053566.1) Inquiry
CDCR346105 Human PTCH1 ORF Clone(NM_001083607.1) Inquiry
CDCR346103 Human PTCH1 ORF Clone(NM_001083606.1) Inquiry
CDCR346099 Human PTCH1 ORF Clone(NM_001083604.1) Inquiry
CDCR246394 Mouse Ptch1 ORF Clone(NM_008957.2) Inquiry
CDCH069360 human PTCH1 ORF clone (NM_001083603.1) Inquiry
CDCH069358 human PTCH1 ORF clone (NM_001083605.1) Inquiry
CDCH069356 human PTCH1 ORF clone (NM_000264.3) Inquiry
CDCH069354 human PTCH1 ORF clone (NM_001083602.1) Inquiry
CDCS407351 Human PTCH1 ORF Clone (BC043542) Inquiry
CDCB166937 Chicken PTCH1 ORF Clone (NM_204960) Inquiry
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