shRNA set against Human PTCH1 (NM_000264.3)

Name: shRNA set against Human PTCH1 (NM_000264.3)
SKU: SHH385820
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH385820

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Product Information

Gene Information

Cat. No.	SHH385820
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	PTCH1
Gene Name	PTCH1 patched 1 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	PTCH1 patched 1 [ Homo sapiens ]
Gene Symbol	PTCH1
Synonyms	PTC; BCNS; HPE7; PTC1; PTCH; NBCCS; PTCH11
Gene Description	patched homolog 1 (Drosophila)
Gene ID	5727
Uni Prot ID	Q13635
m RNA Refseq	NM_000264.3
Protein Refseq	NP_000255.2
Chromosome Location	9q22.3
Function	cholesterol binding; cyclin binding; hedgehog family protein binding; hedgehog receptor activity; heparin binding; patched binding; protein binding; protein complex binding; smoothened binding;
Pathway	Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Glypican 3 network, organism-specific biosystem; Hedgehog Signaling Pathway, organism-specific biosystem;
MIM	601309

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