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Panoply™ Human PTCH1 Knockdown Stable Cell Line

Cat.No.
CSC-DC012642
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PTCH1
Synonyms
PTC; BCNS; HPE7; PTC1; PTCH; NBCCS; PTCH11
Gene Description
patched homolog 1 (Drosophila)
Gene ID
UniProt ID
Q13635
mRNA Refseq
Protein Refseq
Chromosome Location
9q22.3
Function
cholesterol binding; cyclin binding; hedgehog family protein binding; hedgehog receptor activity; heparin binding; patched binding; protein binding; protein complex binding; smoothened binding;
Pathway
Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Glypican 3 network, organism-specific biosystem; Hedgehog Signaling Pathway, organism-specific biosystem;
MIM

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