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shRNA set against Human PPARA (NM_005036.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH380324

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Gene Information

Cat. No. SHH380324
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr PPARA
Gene Name PPARA peroxisome proliferator-activated receptor alpha [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name PPARA peroxisome proliferator-activated receptor alpha [ Homo sapiens ]
Gene Symbol PPARA
Synonyms PPAR; NR1C1; hPPAR; PPARalpha
Gene Description peroxisome proliferator-activated receptor alpha
GeneID 5465
Uni ProtID F1D8S4
mRNA Refseq NM_001001928.2
Protein Refseq NP_001001928.1
Chromosome Location 22q13.31
Function DNA binding; RNA polymerase II repressing transcription factor binding; drug binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; lipid binding; protein binding; protein domain specific binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; ubiquitin conjugating enzyme binding; zinc ion binding;
Pathway Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem;
MIM 170998
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