Rat Ppara ORF Clone(NM_013196.1)

Name: Rat Ppara ORF Clone(NM_013196.1)
SKU: CDCR378079
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR378079

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Product Information

Gene Information

Cat. No.	CDCR378079
Product Type	ORF Clone
Gene Abbr	Ppara
Species	Rat
Tag	C-terminal Myc-DDK
ORF Size	1407 bp
Vector	pCMV6-Entry

Target Gene

PPARA

Background

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]

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