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Panoply™ Human PPARA Knockdown Stable Cell Line

Cat.No.
CSC-DC012171
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PPARA
Synonyms
PPAR; NR1C1; hPPAR; PPARalpha
Gene Description
peroxisome proliferator-activated receptor alpha
Gene ID
UniProt ID
F1D8S4
mRNA Refseq
Protein Refseq
Chromosome Location
22q13.31
Function
DNA binding; RNA polymerase II repressing transcription factor binding; drug binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; lipid binding; protein binding; protein domain specific binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; ubiquitin conjugating enzyme binding; zinc ion binding;
Pathway
Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem;
MIM

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