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shRNA set against Human CACNA1C (NM_000719.6)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH253273

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Gene Information

Cat. No. SHH253273
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CACNA1C
Gene Name CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit [ Homo sapiens ]
Gene Symbol CACNA1C
Synonyms TS; LQT8; CACH2; CACN2; CaV1.2; CCHL1A1; CACNL1A1
Gene Description calcium channel, voltage-dependent, L type, alpha 1C subunit
GeneID 775
Uni ProtID Q13936
mRNA Refseq NM_001129838.1
Protein Refseq NP_001123310.1
Chromosome Location 12p13.3
Function alpha-actinin binding; calmodulin binding; protein binding; protein domain specific binding; protein phosphatase 2A binding; voltage-gated calcium channel activity;
Pathway Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem;
MIM 114205
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