Rat Cacna1c cDNA Clone(NM_012517.2)

Name: Rat Cacna1c cDNA Clone(NM_012517.2)
SKU: CDFR010194
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR010194

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Product Information

Gene Information

Cat. No.	CDFR010194
Description	NativeORF clone of Rattus norvegicus calcium channel, voltage-dependent, L type, alpha 1C subunit (Cacna1c) as transfection-ready DNA NM_012517.2
Product Type	cDAN Clone
Gene Abbr	Cacna1c
Species	Rat
Vector	pCMV6Entry

Target Gene

CACNA1C

Background

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]

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