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Rat Cacna1c ORF Clone(NM_012517.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR377425

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Gene Information

Cat. No. CDCR377425
Product Type ORF Clone
Gene Abbr Cacna1c
Species Rat
Tag C-terminal Myc-DDK
ORF Size 6513 bp
Vector pCMV6-Entry
Target Gene CACNA1C
Background This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
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