shRNA set against Human BRCA2 (NM_000059.3)

Name: shRNA set against Human BRCA2 (NM_000059.3)
SKU: SHH247558
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH247558

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Product Information

Gene Information

Cat. No.	SHH247558
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	BRCA2
Gene Name	BRCA2 breast cancer 2, early onset [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	BRCA2 breast cancer 2, early onset [ Homo sapiens ]
Gene Symbol	BRCA2
Synonyms	FAD; FACD; FAD1; GLM3; BRCC2; FANCB; FANCD; PNCA2; FANCD1; BROVCA2
Gene Description	breast cancer 2, early onset
Gene ID	675
Uni Prot ID	P51587
m RNA Refseq	NM_000059.3
Protein Refseq	NP_000050.2
Chromosome Location	13q12.3
Function	H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; gamma-tubulin binding; NOT histone acetyltransferase activity; protease binding; protein binding; single-stranded DNA binding;
Pathway	DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; FOXM1 transcription factor network, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem;
MIM	600185

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