Resiquimod

Name: Resiquimod
SKU: VAR-026

For research use only. Not intended for any clinical use.

Cat.No.

VAR-026

Description

Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages, and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors.

Alias

R848; S28463

Product Type

Toll-like Receptor Agonists

Storage

Store at 4°C.

Publications

Q & A

Customer Reviews

Customer Q&As

What receptor is the Resiquimod an agonist for?

A: Resiquimod is an agonist for Toll-like receptors 7 and 8 (TLR7/TLR8), inducing the upregulation of cytokines such as TNF-α, IL-6, and IFN-α.

How can the Resiquimod be applied?

A: Resiquimod can be used for animal modeling, constructing mouse cytokine release models, and immune-mediated heart tissue injury models.

How is the stock solution prepared?

A: Please choose a suitable solvent for preparing the stock solution based on the product's solubility in different solvents. Once prepared, please aliquot and store to avoid repeated freeze-thaw cycles that may lead to product deterioration.

What should be done if there is precipitation during the preparation of the stock solution?

A: If precipitation or precipitation occurs during preparation, it can be assisted in dissolution by heating and/or ultrasound.

What is the purity of the Resiquimod?

A: The purity is high, at 99.96%.

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