Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : VAR-030
| Cat. No. | VAR-030 |
| Description | CL075 is a selective agonist of Toll-like receptor 8 (TLR8) with immunostimulant activity. CL075 can Induce production of TNF-α and IL-12 from peripheral blood mononuclear cells (PBMCs). |
| Product Type | Toll-like Receptor Agonists |
| Alias | 2-Propylthiazolo[4,5-c]quinolin-4-amine, 3M002 |
| Purity | ≥98% |
| Storage | Store at 4°C. |
A: CL075 triggers MyD88-dependent signaling pathway, which activates the production of inflammatory cytokines and type I interferon (IFN) by inducing NF-B and IRF7.
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CL075 can induce the production of TNF-α and IL-12 in peripheral blood mononuclear cells (PBMC).
We have successfully activated Toll-like receptor 8 in rabbits using this reagent.
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