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CL075

For research use only. Not intended for any clinical use.

Cat. No. :   VAR-030

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Product Information

Cat. No. VAR-030
Description CL075 is a selective agonist of Toll-like receptor 8 (TLR8) with immunostimulant activity. CL075 can Induce production of TNF-α and IL-12 from peripheral blood mononuclear cells (PBMCs).
Product Type Toll-like Receptor Agonists
Alias 2-Propylthiazolo[4,5-c]quinolin-4-amine, 3M002
Purity ≥98%
Storage Store at 4°C.
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What substance can CL075 stimulate cells to produce?

A: CL075 triggers MyD88-dependent signaling pathway, which activates the production of inflammatory cytokines and type I interferon (IFN) by inducing NF-B and IRF7.

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Peripheral blood mononuclear cells

CL075 can induce the production of TNF-α and IL-12 in peripheral blood mononuclear cells (PBMC).

United States

Toll-like receptor 8

We have successfully activated Toll-like receptor 8 in rabbits using this reagent.

United States

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