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Recombinant Mouse CD38 (C-6His)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00173 Tag :   C-6His

Expressed Region :   Leu45-Thr304 Expression System :   Human Cell

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Product Information

Gene Information

Cat. No. RP00173
Description The Recombinant Mouse CD38 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Leu45-Thr304 with a 6His tag at the C terminus.
Species Mouse
Tag C-6His
Mol Weight 30.6 KDa
Conjugate Unconjugated
Format Liquid
Expressed Region Leu45-Thr304
Expression System Human Cell
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Purity >95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Endotoxin Level < 1 EU/µg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Target Gene Cd38
Synonyms ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD38
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The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

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