Recombinant Human CD38 (C-6His)

Name: Recombinant Human CD38 (C-6His)
SKU: RP00033

Cat.No. : RP00033 Tag: C-6His

Expressed Region: Val43-Ile300 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00033
Description	The Recombinant Human CD38 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Val43-Ile300 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol. Weight	30.7 KDa
Expressed Region	Val43-Ile300
Expression System	Human Cell
Format	Liquid
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.

Target Gene	CD38
Background	The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.
Synonyms	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule;CD38

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