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Cat. No. : RP00211 Tag : C-6His
Expressed Region : Cys32-His430 Expression System : Human Cell
| Cat. No. | RP00211 |
| Description | The Recombinant Human TrkB (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Cys32-His430 with a 6His tag at the C terminus. |
| Species | Human |
| Tag | C-6His |
| Mol Weight | 45.25 KDa |
| Conjugate | Unconjugated |
| Format | Powder |
| Expressed Region | Cys32-His430 |
| Expression System | Human Cell |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| Purity |
>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
| Endotoxin Level | < 1 EU/µg of protein by LAL method |
| Storage | Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below. |
| Reconstitution | Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Target Gene | TrkB |
| Background | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. |
| Synonyms | BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine Kinase Receptor Type 2; TrkB Tyrosine Kinase; Tropomyosin-Related Kinase B; NTRK2; TRKB |
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