Human NTRK2(His) HEK293 Cell Lysate

Name: Human NTRK2(His) HEK293 Cell Lysate
SKU: CLOE-1780
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1780 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1780
Introduction	This cell lysate over-expresses C-terminal polyhistidine tagged human NTRK2 (NP_001007098.1) (Met 1-His 430). Purification of target protein (s) from this cell lysate has been verified.
Target Gene	NTRK2
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	NTRK2 neurotrophic tyrosine kinase, receptor, type 2 [ Homo sapiens ]
Gene Symbol	NTRK2
Synonyms	TRKB; trk-B; GP145-TrkB
Gene Description	neurotrophic tyrosine kinase, receptor, type 2
Gene ID	4915
Uni Prot ID	Q16620
m RNA Refseq	NM_006180.3
Protein Refseq	NP_006171.2
Chromosome Location	9q22.1
Function	ATP binding; brain-derived neurotrophic factor binding; brain-derived neurotrophic factor-activated receptor activity; neurotrophin binding; neurotrophin binding; protein homodimerization activity;
Pathway	Activation of TRKA receptors, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; NGF signalling via TRKA from the plasma membrane, organism-specific biosystem; NGF-independant TRKA activation, organism-specific biosystem;
MIM	600456

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