Recombinant Human TIGIT (C-mFc)

Name: Recombinant Human TIGIT (C-mFc)
SKU: RP00186
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00186 Tag : C-mFc

Expressed Region : Met22-Pro141 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00186
Description	The Recombinant Human TIGIT (C-mFc) is produced in our Human Cell expression system. The amino acid region expressed is Met22-Pro141 with a mFc tag at the C terminus.
Species	Human
Tag	C-mFc
Mol Weight	39.7 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Met22-Pro141
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	TIGIT
Background	This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Synonyms	T-cell immunoreceptor with Ig and ITIM domains; VSIG9; VSTM3; TIGIT; V-set and transmembrane domain-containing protein 3; V-set and immunoglobulin domain-containing protein 9

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