Recombinant Human MerTK (C-6His)

Name: Recombinant Human MerTK (C-6His)
SKU: RP00220
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00220 Tag : C-6His

Expressed Region : Met1-Ala323 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00220
Description	The Recombinant Human MerTK (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Met1-Ala323 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	36 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Met1-Ala323
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	MerTK
Background	This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Synonyms	Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; MERTK; MER

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