Humanized MERTK Murine Tumor Cell Line

Name: Humanized MERTK Murine Tumor Cell Line
SKU: CSC-RH0075M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0075M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0075M
Description	This cell line is engineered to stably express chimeric MERTK containing human signal peptide, extracellular domain, transmembrane domain and mouse cytoplasmic domain. The endogenous mouse Mertk gene was disrupted, resulting in a non-functional transcript.
Target Gene	MERTK
Alias	MER, RP38, Tyro12, c-Eyk, c-mer
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MERTK c-mer proto-oncogene tyrosine kinase [ Homo sapiens ]
Gene Symbol	MERTK
Synonyms	MER; RP38; c-mer
Gene Description	c-mer proto-oncogene tyrosine kinase
GeneID	10461
Uni ProtID	Q12866
mRNA Refseq	NM_006343.2
Protein Refseq	NP_006334.2
Chromosome Location	2q14.1
Function	ATP binding; protein binding; transmembrane receptor protein tyrosine kinase activity;
Pathway	Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem;
MIM	604705

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