Recombinant Human ACVR2A (C-Fc-6His)

Name: Recombinant Human ACVR2A (C-Fc-6His)
SKU: RP00311

Cat.No. : RP00311 Tag: C-Fc-6His

Expressed Region: Ala20-Pro134 Expression System: Human Cell

Inquire for Price

Product Details

Target Information

Cat. No.	RP00311
Description	The Recombinant Human ACVR2A (C-Fc-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ala20-Pro134 with a Fc-6His tag at the C terminus.
Species	Human
Tag	C-Fc-6His
Mol. Weight	41.2 KDa
Expressed Region	Ala20-Pro134
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	ACVR2A
Background	This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
Synonyms	Activin Receptor Type-2A; Activin Receptor Type IIA; ACTR-IIA; ACTRIIA; ACVR2A; ACVR2

Quick Inquiry

Publications

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

First Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *