Human ACVR2A HEK293 Cell Lysate

Name: Human ACVR2A HEK293 Cell Lysate
SKU: CLOE-1569
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1569 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1569
Introduction	This cell lysate over-expresses human ACVR2A (NP_001607.1) (Met 1-Pro 134) fused with the Fc region of human IgG1 at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	ACVR2A
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	ACVR2A activin A receptor, type IIA [ Homo sapiens ]
Gene Symbol	ACVR2A
Synonyms	ACVR2; ACTRII
Gene Description	activin A receptor, type IIA
Gene ID	92
Uni Prot ID	P27037
m RNA Refseq	NM_001616.3
Protein Refseq	NP_001607.1
Chromosome Location	2q22.3
Function	ATP binding; PDZ domain binding; contributes_to activin binding; activin receptor activity, type II; contributes_to activin-activated receptor activity; coreceptor activity; growth factor binding; inhibin binding; metal ion binding; protein binding; contributes_to protein binding; protein self-association; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;
Pathway	ALK1 signaling events, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Developmental Biology, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem;
MIM	102581

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