Biotinylated Human NRP1 (C-Avi-6His)

Name: Biotinylated Human NRP1 (C-Avi-6His)
SKU: RP00618
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00618 Tag : C-Avi-6His

Expressed Region : Phe22-Lys644 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00618
Description	Biotinylated Human NRP1 (C-Avi-6His) is produced in our Human Cell expression system. The amino acid region expressed is Phe22-Lys644 with a Avi-6His tag at the C terminus.
Species	Human
Tag	C-Avi-6His
Mol Weight	72.5 KDa
Conjugate	Biotinylated
Format	Powder
Expressed Region	Phe22-Lys644
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	NRP1
Synonyms	CD304; NRP1; NRPNP1; VEGF165R; BDCA4

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This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.

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