Rat Nrp1 cDNA Clone(NM_145098.2)

Name: Rat Nrp1 cDNA Clone(NM_145098.2)
SKU: CDFR014481
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014481

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Product Information

Gene Information

Cat. No.	CDFR014481
Description	NativeORF clone of Rattus norvegicus neuropilin 1 (Nrp1) as transfection-ready DNA NM_145098.2
Product Type	cDAN Clone
Gene Abbr	Nrp1
Species	Rat
Vector	pCMV6Entry

Target Gene

NRP1

Background

This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Nov 2020]

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