Monophosphoryl Lipid A from E. coli R515

Name: Monophosphoryl Lipid A from E. coli R515
SKU: VAR-022
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : VAR-022

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Product Information

Cat. No.	VAR-022
Description	Monophosphoryl lipid A (MPL), is a chemically modified derivative of lipopolysaccharide that displays greatly reduced toxicity while maintaining most of the immunostimulatory activity of lipopolysaccharide. MPL has been shown to be capable of binding and activating Toll-like receptor 4 (TLR4), present on key antigen-presenting cells, which play an important role in the induction of the innate and subsequent adaptive immune responses. It has been used extensively in clinical trials as a component in prophylactic and therapeutic vaccines targeting infectious disease, cancer and allergies.
Product Type	Bacteria-derived Adjuvant
Stability	Stable for at least 2 years after receipt when stored at 4°C.
Purity	≥99%
Storage	Store at 4°C;

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Is Monophosphoryl Lipid A from E. coli R515 LPS?

A: No, Monophosphoryl Lipid A from E. coli R515 is a chemically modified derivative of lipopolysaccharide, which shows greatly reduced toxicity while retaining most of the immune-stimulating activity of lipopolysaccharide.

Does the reagent only affect innate immune responses?

A: MPL can bind to and activate Toll-like receptor 4 (TLR4), which plays an important role in inducing innate and subsequent adaptive immune responses.

Can the reagent be used for prophylactic and therapeutic measures against infectious diseases and allergies?

A: No, this reagent is only for scientific research and cannot be used for relevant treatments.

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Customer Reviews

Low toxicity

While ensuring immune stimulation activity, its toxicity to cells and organisms is low.

United States

2022-01-31

Door-to-door delivery

The delivery service is convenient, with home delivery available after purchase.

United States

2022-08-05

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Monophosphoryl Lipid A from E. coli R515

Product Information

Q & A

Customer Reviews

Is Monophosphoryl Lipid A from E. coli R515 LPS?

Does the reagent only affect innate immune responses?

Can the reagent be used for prophylactic and therapeutic measures against infectious diseases and allergies?

Low toxicity

Door-to-door delivery

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