Humanized ERBB3 Murine Tumor Cell Line

Name: Humanized ERBB3 Murine Tumor Cell Line
SKU: CSC-RH0034M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0034M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0034M
Description	These transgenic cells carry humanized ERBB3 and form solid tumors in vivo. The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.
Target Gene	ERBB3
Alias	ERBB3, ErbB-3, FERLK, HER3, LCCS2, MDA-BF-1, VSCN1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) [ Homo sapiens ]
Gene Symbol	ERBB3
Synonyms	HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3
Gene Description	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
GeneID	2065
Uni ProtID	P21860
mRNA Refseq	NM_001005915.1
Protein Refseq	NP_001005915.1
Chromosome Location	12q13
Function	ATP binding; growth factor binding; growth factor binding; protein binding; protein heterodimerization activity; protein heterodimerization activity; protein homodimerization activity; protein tyrosine kinase activator activity; NOT protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; transmembrane signaling receptor activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Disease, organism-specific biosystem;
MIM	190151

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