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Human ERBB3(Fc tag) HEK293 Cell Lysate

For research use only. Not intended for any clinical use.

Cat. No. :   CLOE-1625 Host Cell :   HEK293

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Cell Lysate Information

Gene Information

Cat. No. CLOE-1625
Introduction This cell lysate over-expresses the human ERBB3 (NP_001973.2) (Met1-Thr643) fused with the Fc region of human IgG1 at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene ERBB3
Host Cell HEK293
Host Cell Species Homo sapiens (Human)
Applications Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO2. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium Complete medium supplemented with 10% (v/v) DMSO
Storage Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping Ice package
Gene Name ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) [ Homo sapiens ]
Gene Symbol ERBB3
Synonyms HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3
Gene Description v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
GeneID 2065
Uni ProtID P21860
mRNA Refseq NM_001005915.1
Protein Refseq NP_001005915.1
Chromosome Location 12q13
Function ATP binding; growth factor binding; growth factor binding; protein binding; protein heterodimerization activity; protein heterodimerization activity; protein homodimerization activity; protein tyrosine kinase activator activity; NOT protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; transmembrane signaling receptor activity;
Pathway Adaptive Immune System, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Disease, organism-specific biosystem;
MIM 190151
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