human MUTYH (NM_001048172) lentivirus particles

Name: human MUTYH (NM_001048172) lentivirus particles
SKU: LV18868L
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : LV18868L

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	LV18868L
Description	Lentiviral particles of mutY homolog (E. coli) (MUTYH), transcript variant gamma2.
Product Type	Premade Lentivirus Particles
Gene	MUTYH
Species	Human
Insert Size	1569 bp
Titer	Varies lot by lot, for example, ≥110^7 TU/mL, ≥110^8 TU/mL, ≥1*10^9 TU/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma	Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity	Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility	The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility	Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation	All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.

Gene Name	MUTYH mutY homolog (E. coli) [ Homo sapiens ]
Gene Symbol	MUTYH
Synonyms	MYH; CYP2C
Gene Description	mutY homolog (E. coli)
Gene ID	4595
Uni Prot ID	E5KP28
m RNA Refseq	NM_001048172.1
Protein Refseq	NP_001041637.1
Chromosome Location	1p34.1
Function	4 iron, 4 sulfur cluster binding; NOT MutLalpha complex binding; NOT MutLbeta complex binding; MutSalpha complex binding; NOT MutSbeta complex binding; endonuclease activity; hydrolase activity, acting on glycosyl bonds; metal ion binding; protein binding;
Pathway	Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged purine, organism-specific biosystem; DNA Repair, organism-specific biosystem;
MIM	604933

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