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Panoply™ Human MUTYH Knockdown Stable Cell Line

Cat.No.
CSC-DC009949
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
MUTYH
Synonyms
MYH; CYP2C
Gene Description
mutY homolog (E. coli)
Gene ID
UniProt ID
E5KP28
mRNA Refseq
Protein Refseq
Chromosome Location
1p34.1
Function
4 iron, 4 sulfur cluster binding; NOT MutLalpha complex binding; NOT MutLbeta complex binding; MutSalpha complex binding; NOT MutSbeta complex binding; endonuclease activity; hydrolase activity, acting on glycosyl bonds; metal ion binding; protein binding;
Pathway
Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged purine, organism-specific biosystem; DNA Repair, organism-specific biosystem;
MIM

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