human APH1A (NM_016022) lentivirus particles

Name: human APH1A (NM_016022) lentivirus particles
SKU: LV05191L
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : LV05191L

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	LV05191L
Description	Lentiviral particles of anterior pharynx defective 1 homolog A (C. elegans) (APH1A), transcript variant 2.
Product Type	Premade Lentivirus Particles
Gene	APH1A
Species	Human
Insert Size	744 bp
Titer	Varies lot by lot, for example, ≥110^7 TU/mL, ≥110^8 TU/mL, ≥1*10^9 TU/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma	Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity	Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility	The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility	Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation	All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.

Gene Name	APH1A anterior pharynx defective 1 homolog A (C. elegans) [ Homo sapiens ]
Gene Symbol	APH1A
Synonyms	APH1A; anterior pharynx defective 1 homolog A (C. elegans); gamma-secretase subunit APH-1A; APH 1A; CGI 78; aph-1alpha; presenilin-stabilization factor; APH-1; APH-1A; CGI-78; 6530402N02Rik;
Gene ID	51107
Uni Prot ID	Q96BI3
m RNA Refseq	BC008732
Chromosome Location	1p36.13-q31.3
Function	aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity; protein binding;
Pathway	Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; NRIF signals cell death from the nucleus, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem;
MIM	607629

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